Endocrine Abstracts

Introduction: There are many reports that vascular and/or heart valve calcification is good predictor for low bone mineral density. I investigated whether benign calcification of breast can also well predict low bone mineral density.Methods/design: I have reviewed and analyzed the records of 91 women with age more than 50 years old among patients examined bone mineral density and breast mammography from January through December 2010. The lowest value of ...

A 34-year-old lady presented with polyuria and polydipsia 21 months post Caesarian delivery of twins. She had no peri-partum complications but immediately post partum, had noted increased thirst – she noted a particular strong craving for cold soft drinks. She had obesity and a positive family history for diabetes but screening for diabetes was negative. She also noted cessation of her menses. A gynaecologist who assessed her found her to have mild hyperprolactinaemia for...

Aim: Differentiating idiopathic hypogonadotrophic hypogonadism from extreme maturational delay can be difficult, so most boys receive testosterone (T) replacement until the diagnosis becomes clear. Standard 3 month T therapy for maturational delay does not diminish adult stature, so we set out to determine whether T treatment of greater than 6 months duration would have an adverse effect on final height (FH) in boys with the eventual diagnosis of extreme maturational delay.</p...

Objective: Patients with thyroiditis often have sialadenitis. Radioactive iodine therapy (RAIT) sialadenitis could lower the patient’s quality of life. However, it had not been investigated about the occurrence of RAIT sialadenitis and the presence of underlying thyroiditis. Therefore, we analyzed the preoperative thyroid ultrasound (US) with radiomics to figure out the occurrence of the RAIT sialadenitis.Materials and Methods: In this retrospective...

Leydig cell tumors are a rare form of hormonally active testicular tumors. They often present as a painless testicular mass. Infertility as the primary presentation is rare in this condition. A 32 year old man, presented with symptoms of infertility and hypogonadism which had occurred over a period of 1 year. He however was found to have a raised testosterone and estradiol levels as well as suppressed gonadotrophin levels. The patient had a historic sperm analysis done 2 years...

Introduction: Testosterone Replacement Therapy (TRT) is used for aged-related or other forms of hypogonadism and prostatic specific antigen (PSA) is primary screening tool for prostatic cancer in men. The European Academy of Andrology guidelines on investigation, treatment and monitoring of functional hypogonadism in males (EAA-TRT) endorsed by European Society of Endocrinology (ESE) states Recommendation #31. We suggest performing digital rectal examination and checking P...

Pregabalin is a highly used drug for the effective treatment of diabetic neuropathic pain. This study compared the efficacy and safety of a controlled-release (CR) Pregabalin tablet (GLA5PR GLARS-NF1) with an immediate-release (IR) Pregabalin capsuleafter 12 week administration in patients with diabetic peripheral neuropathy. In multicenter, randomized, double- blind, active- controlled, parallel- group, phase III study, the primary outcome was to confirm that CR pregabalin wi...

Background: Higher body weight is associated with greater bone mineral density (BMD). Lean mass (LM) is positively related with bone parameters in adolescence. However, a number of controversial studies have suggested that fat mass (FM) has beneficial effect or has detrimental effect on BMD in adolescence. These contradictory results of FM on bone parameters might be developed by the non-linear relationship in the adolescent population.Objective: We eval...

Purpose: This retrospective study is intended to determine the dose of radioactive iodine using thyroglobulin levels measured after two weeks of thyroid hormone withdrawal in patients with differentiated thyroid cancer. Methods : Patients who were diagnosed as differentiated thyroid cancer and treated with radioiodine after total thyroidectomy were enrolled. Serum thyroglobulin test (preTG; ng/dl) was performed 1 week before radioiodine treatment and 2 w...

Hemorrhagic fever with renal syndrome (HFRS) is a severe systemic infection caused by hantaviruses that included Hantaan, Seoul, Dobrava, Saaremaa, and Puumala. In Korea, the most common virus is Hantaan. The classical symptoms of HFRS are fever, hemorrhage, hypotension, and renal failure, but the clinical course can be very diverse. Among them, endocrinologic complications, such as hypopituitarism were developed rarely by HFRS. A 49 years-old man admitted our hospital with fe...